Endocrine Abstracts

The European Registry on Cushing’s syndrome (ERCUSYN) is a project aimed at gathering data at EU level on clinical features, diagnostic procedures and therapeutic strategies in CS patients. The creation of this large European database is expected to provide comprehensive information on all stages of the disease from the first diagnosis to long-term follow-up. This ultimately should result in earlier recognition of CS and all its co-morbidities, and assist clinicians in co...

Objective: To evaluate the outcome of preoperative therapy with ketoconazole (KTZ) and/or metyrapone (MTP), in previously untreated CS patients who later underwent surgery.Design and methods: A total of 62 CS patients (85% ACTH-dependent), who have been treated with steroidogenesis inhibitors prior to surgery in our centre between 1983 and 2010, were retrospectively studied. T0 and t1 defined visit at baseline and at the end of medical treatment, respect...